hydrolase$36458$ - significado y definición. Qué es hydrolase$36458$
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Qué (quién) es hydrolase$36458$ - definición

MAMMALIAN PROTEIN FOUND IN HOMO SAPIENS
Kynurenine hydrolase; KYNU (gene); EC 3.7.1.3; L-kynurenine hydrolase
  • <div style="border-width: 0px; border-bottom: 1px solid black; text-align: left;">'''The KYNU's reaction mechanism'''.</div>The color scheme is as follows: <span style="font-weight: bold;"><span style="color: blue;">KYNU</span>, <span style="color: rgb(219,155,36);">PLP</span>, <span style="color: rgb(151,149,45);">substrate names</span>, <span style="color: rgb(128,0,0);">inorganic molecules</span>, <span style="color: red;">3hAn's moiety</span>, <span style="color: rgb(230,192,230);">Ala's moiety</span> </span>

Alpha/beta hydrolase superfamily         
INTERPRO DOMAIN
Alpha/beta hydrolase; Α/β hydrolase fold; Α/β hydrolase; Alpha/beta hydrolase fold; AB hydrolase
The alpha/beta hydrolase superfamily is a superfamily of hydrolytic enzymes of widely differing phylogenetic origin and catalytic function that share a common fold. The core of each enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 beta strands connected by 6 alpha helices.
Ubiquitinyl hydrolase 1         
CLASS OF ENZYMES
EC 3.4.19.12; Yeast ubiquitin hydrolase
Ubiquitinyl hydrolase 1 (, ubiquitin C-terminal hydrolase, yeast ubiquitin hydrolase) is an enzyme. This enzyme catalyses the following chemical reaction
Limonene-1,2-epoxide hydrolase         
  • 500x500px
  • A diagram of the products of limonene-1,2-epoxide hydrolase
CLASS OF ENZYMES
EC 3.3.2.8; 1,2-epoxymeth-8-ene hydrolase
In enzymology, a limonene-1,2-epoxide hydrolase () is an enzyme that catalyzes the chemical reaction

Wikipedia

Kynureninase

Kynureninase or L-Kynurenine hydrolase (KYNU) (EC 3.7.1.3) is a PLP dependent enzyme that catalyses the cleavage of kynurenine (Kyn) into anthranilic acid (Ant). It can also act on 3-hydroxykynurenine (to produce 3-hydroxyanthranilate) and some other (3-arylcarbonyl)-alanines. Humans express one kynureninase enzyme that is encoded by the KYNU gene located on chromosome 2.

KYNU is part of the pathway for the catabolism of Trp and the biosynthesis of NAD cofactors from tryptophan (Trp).

Kynureninase catalyzes the following reaction:

L-kynurenine + H2O ↔ anthranilate + L-alanine